Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5662592 | 1.00 | HRH3 (0.52) | HRH3KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL4423115 | 0.92 | KDM4E (0.47) | HRH3KMT2AKDM4EALDH1A1 | |
| SCHEMBL14392597 | 0.92 | KDM4E (0.47) | HRH3KMT2AKDM4EALDH1A1 | |
| SCHEMBL4423112 | 0.92 | KDM4E (0.47) | HRH3KMT2AKDM4EALDH1A1 | |
| SCHEMBL14368967 | 0.89 | KMT2A (0.52) | HRH3KMT2AALDH1A1HPGD | |
| SCHEMBL14368976 | 0.84 | ALDH1A1 (0.47) | HRH3KDM4EALDH1A1 | |
| SCHEMBL14392706 | 0.84 | CCR3 (0.49) | KDM4E | |
| SCHEMBL28779154 | 0.83 | ALDH1A1 (0.53) | HRH3KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL14368810 | 0.83 | ALDH1A1 (0.53) | HRH3KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL14368980 | 0.83 | ALDH1A1 (0.47) | HRH3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |