Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757692 | 0.93 | S1PR1 (0.35) | S1PR1S1PR5PTGS2SIGMAR1CYP3A4 | |
| SCHEMBL27757695 | 0.91 | SPHK1 (0.37) | S1PR1S1PR5PTGS2SIGMAR1S1PR3 | |
| Hydrochloric Acid SCHEMBL6376023 | 0.89 | S1PR1 (0.37) | S1PR1S1PR5PTGS2SIGMAR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL27463582 | 0.85 | PTGS2 (0.38) | S1PR1S1PR5PTGS2CTSSCTSK | |
| SCHEMBL27795394 | 0.85 | S1PR1 (0.35) | S1PR1S1PR5PTGS2SIGMAR1CYP3A4 | |
| SCHEMBL7037699 | 0.84 | S1PR1 (0.40) | S1PR1S1PR5PTGS2SIGMAR1CTSS | |
| Hydrochloric Acid SCHEMBL14812064 | 0.84 | S1PR1 (0.34) | S1PR1S1PR5PTGS2SIGMAR1CYP3A4 | |
| SCHEMBL7194351 | 0.84 | S1PR1 (0.34) | S1PR1S1PR5PTGS2CTSSCTSK | |
| SCHEMBL7105433 | 0.83 | S1PR1 (0.35) | S1PR1S1PR5PTGS2SIGMAR1CTSS | |
| SCHEMBL27586776 | 0.83 | S1PR1 (0.35) | S1PR1S1PR5PTGS2CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356199-A | Method for producing ultra-high molecular weight polymers by means of special bridged metallocene catalysts | TICONA GMBH (DE) | 2009-01-28 | — | — | CN | disclosed |