Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | ATM | Q13315 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MAX | P61244 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13777318 | 0.83 | CYP2C19 (0.60) | KDM4EPOLBHSD17B10HPGDALOX15 | |
| 2-Methylaminobenzoic Acid Methyl Ester SCHEMBL165559 | 0.81 | KDM4E (1.00) | KDM4EATMPOLBHSD17B10HPGD | |
| 2-Methylaminobenzoic Acid Methyl Ester SCHEMBL29364831 | 0.81 | KDM4E (1.00) | KDM4EATMPOLBHSD17B10HPGD | |
| SCHEMBL10941978 | 0.81 | MAPT (0.70) | KDM4EHSD17B10HPGDALOX15MAPT | |
| SCHEMBL29437924 | 0.80 | HSD17B10 (0.76) | KDM4EATMHSD17B10HPGDALOX15 | |
| SCHEMBL69868 | 0.80 | HSD17B10 (0.76) | KDM4EATMHSD17B10HPGDALOX15 | |
| SCHEMBL9340558 | 0.79 | HSD17B10 (0.63) | KDM4EATMPOLBHSD17B10HPGD | |
| 2-Methylaminobenzoic Acid Methyl Ester SCHEMBL29271837 | 0.79 | KDM4E (0.96) | KDM4EATMPOLBHSD17B10HPGD | |
| SCHEMBL8121709 | 0.79 | HSD17B10 (0.54) | KDM4EATMPOLBHSD17B10HPGD | |
| SCHEMBL28201066 | 0.79 | HPGD (0.68) | KDM4EHSD17B10HPGDALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101360707-A | Thrombopoietin activity modulating compounds and methods | LIGAND PHARM INC (US) | 2009-02-04 | — | — | CN | claimed |
| CN-101360707-A | Thrombopoietin activity modulating compounds and methods | LIGAND PHARM INC (US) | 2009-02-04 | — | — | CN | disclosed |