Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MAX | P61244 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104888 | 0.88 | PTK2B (0.54) | HSD17B10HPGDMAPTKDM4EALDH1A1 | |
| SCHEMBL8107951 | 0.85 | RAB9A (0.49) | HSD17B10HPGDMAPTKDM4EALDH1A1 | |
| SCHEMBL8116289 | 0.84 | ALOX15 (0.60) | HSD17B10ALOX15MAPTALDH1A1KMT2A | |
| SCHEMBL8121943 | 0.82 | MAPK1 (0.43) | HSD17B10HPGDALOX15MAPTTSHR | |
| SCHEMBL29483352 | 0.81 | KDM4E (0.65) | HSD17B10HPGDALOX15MAPTTSHR | |
| SCHEMBL2442267 | 0.81 | KDM4E (0.65) | HSD17B10HPGDALOX15MAPTTSHR | |
| SCHEMBL28528095 | 0.79 | KDM4E (0.62) | HSD17B10HPGDALOX15MAPTTSHR | |
| SCHEMBL27759453 | 0.79 | KDM4E (0.68) | HSD17B10HPGDALOX15MAPTTSHR | |
| SCHEMBL8116713 | 0.78 | NPSR1 (0.47) | HSD17B10HPGDMAPTTSHRKDM4E | |
| SCHEMBL29413047 | 0.78 | ALDH1A1 (0.57) | HSD17B10HPGDALOX15MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |