Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27759813 | 1.00 | LMNA (0.55) | LMNAL3MBTL1LPAR1LPAR3CTRC | |
| SCHEMBL27739171 | 0.88 | KMT2A (0.48) | LMNAL3MBTL1 | |
| SCHEMBL27739165 | 0.88 | KMT2A (0.48) | LMNAL3MBTL1 | |
| SCHEMBL27759839 | 0.88 | KMT2A (0.48) | LMNAL3MBTL1 | |
| SCHEMBL2716599 | 0.85 | LMNA (0.68) | LMNAL3MBTL1NR1H4ALDH1A1 | |
| SCHEMBL27900716 | 0.83 | LMNA (0.65) | LMNAL3MBTL1NR1H4ALDH1A1 | |
| SCHEMBL2348796 | 0.82 | LMNA (0.55) | LMNAL3MBTL1NR1H4ALDH1A1 | |
| SCHEMBL6311563 | 0.82 | LMNA (0.64) | LMNAL3MBTL1NR1H4ALDH1A1 | |
| SCHEMBL22497335 | 0.81 | LMNA (0.57) | LMNAL3MBTL1CTRCNR1H4ALDH1A1 | |
| SCHEMBL28842185 | 0.81 | LMNA (0.57) | LMNAL3MBTL1CTRCNR1H4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101407459-B | Monohydroxy-2-acyl phenylacetate, and preparation and use thereof | UNIV XIAMEN | 2013-03-27 | — | — | CN | disclosed |
| CN-101407459-A | Monohydroxy-2-acyl phenylacetate, and preparation and use thereof | UNIV XIAMEN (CN) | 2009-04-15 | — | — | CN | disclosed |