Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001653 | 0.83 | KMT2A (0.75) | KDM4EKMT2AHTTNR1H3EGFR | |
| SCHEMBL529976 | 0.82 | KDM4E (0.71) | KDM4EKMT2AHTTNR1H3EGFR | |
| SCHEMBL27877391 | 0.80 | SMN1; SMN2 (0.66) | KDM4EHTTEGFRRAB9ASMN1; SMN2 | |
| SCHEMBL493114 | 0.79 | KMT2A (0.75) | KDM4EKMT2AHTTNR1H3EGFR | |
| SCHEMBL177749 | 0.79 | KMT2A (0.60) | KDM4EKMT2AHTTNR1H3EGFR | |
| SCHEMBL28867918 | 0.78 | KMT2A (0.64) | KDM4EKMT2AHTTNR1H3EGFR | |
| SCHEMBL9567794 | 0.78 | KMT2A (0.68) | KDM4EKMT2AHTTNR1H3EGFR | |
| SCHEMBL2469395 | 0.76 | KMT2A (0.66) | KDM4EKMT2AHTTNR1H3EGFR | |
| SCHEMBL257767 | 0.76 | KMT2A (0.66) | KDM4EKMT2AHTTNR1H3EGFR | |
| SCHEMBL22575409 | 0.76 | HTT (0.70) | KDM4EKMT2AHTTNR1H3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230971-B | Boric acid and ester as inhibitors of fatty amide hydrolase | 英菲尼提制药公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-101563089-A | Boronic acids and esters as inhibitors of fatty amide hydrolase | INFINITY DISCOVERY INC (US) | 2009-10-21 | — | — | CN | disclosed |