SCHEMBL529976

SCHEMBL529976

COc1ccc(C(=O)N(C)c2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.71
HPGD P15428 1/20 0.71
HSD17B2 P37059 3/20 0.68
HSD17B1 P14061 2/20 0.68
HTT P42858 2/20 0.60
KMT2A Q03164 2/20 0.60
ALDH1A1 P00352 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2C9 P11712 1/20 0.60
ALOX12 P18054 1/20 0.60
CYP2C19 P33261 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
APP P05067 1/20 0.58
CES2 O00748 1/20 0.58
CES1 P23141 1/20 0.58
NR1H3 Q13133 1/20 0.55
EGFR P00533 1/20 0.55
ERBB2 P04626 1/20 0.55
MCHR1 Q99705 2/20 0.54
NPC1 O15118 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8703995 0.93 KDM4E (0.61) KDM4EHPGDHSD17B2HSD17B1HTT
SCHEMBL6806574 0.91 HSD17B1 (0.65) KDM4EHPGDHSD17B2HSD17B1HTT
SCHEMBL5582735 0.88 CA1 (0.67) KDM4EHPGDHSD17B2HSD17B1HTT
SCHEMBL9001653 0.87 KMT2A (0.75) KDM4EHPGDHTTKMT2AALDH1A1
SCHEMBL6796131 0.85 HSD17B2 (0.91) KDM4EHPGDHSD17B2HSD17B1HTT
SCHEMBL4090142 0.85 HSD17B1 (0.58) KDM4EHPGDHSD17B2HSD17B1HTT
SCHEMBL11371286 0.84 ALDH1A1 (0.53) KDM4EHPGDHSD17B2HSD17B1HTT
SCHEMBL2111928 0.84 KDM4E (0.73) KDM4EHPGDHSD17B2HSD17B1HTT
SCHEMBL7376311 0.83 HSD17B1 (0.57) KDM4EHPGDHSD17B2HSD17B1HTT
SCHEMBL17213443 0.83 HPGD (0.62) HPGDHSD17B2HSD17B1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012014127-A1 5-LIPOXYGENASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2012-02-02 WO claimed
CN-117024295-B Photo-induced amide dealkylation method and application thereof 广州中医药大学(广州中医药研究院) 2025-06-13 CN disclosed
CN-117024295-A Photo-induced amide dealkylation method and application thereof 广州中医药大学(广州中医药研究院) 2023-11-10 CN disclosed
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-9563075-B2 Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate Konica Minolta, Inc. (JP) 2017-02-07 US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 US disclosed
US-9195090-B2 Polymer film, optically-compensatory film, process for producing the same, polarizing plate and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-11-24 US disclosed
US-9097837-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2015-08-04 US disclosed
US-20070273815-A1 Cellulose acylate film, production method of cellulose acylate film, optically-compensatory film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2007-11-29 US disclosed
US-20070259134-A1 Cellulose Compound Film, Optical Compensation Sheet, Polarizing Plate, and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-11-08 US disclosed
US-20070259134-A1 Cellulose Compound Film, Optical Compensation Sheet, Polarizing Plate, and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-11-08 US disclosed
US-20070195226-A1 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2007-08-23 US disclosed
US-20070195226-A1 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2007-08-23 US disclosed
WO-2007061139-A1 CELLULOSE ACYLATE FILM, METHOD OF PRODUCING THE SAME, CELLULOSE DERIVATIVE FILM, OPTICALLY COMPENSATORY FILM USING THE SAME, OPTICALLY-COMPENSATORY FILM INCORPORATING POLARIZING PLATE, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-05-31 WO disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed