SCHEMBL27760244

SCHEMBL27760244

OB(O)Oc1ccc(Oc2cccc(F)c2)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.44
FFAR4 Q5NUL3 2/20 0.44
PPARA Q07869 6/20 0.40
PPARD Q03181 4/20 0.40
KMO O15229 1/20 0.39
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP9 P14780 1/20 0.38
MMP14 P50281 1/20 0.38
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
ERBB3 P21860 1/20 0.38
ERBB4 Q15303 1/20 0.38
KCNH2 Q12809 4/20 0.37
SLC6A4 P31645 4/20 0.37
HTR2A P28223 3/20 0.37
MRGPRX4 Q96LA9 1/20 0.37
PPARG P37231 3/20 0.36
SCN9A Q15858 1/20 0.36
SCN3A Q9NY46 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27781801 0.85 FFAR4 (0.40) FFAR1FFAR4MMP2MMP3MMP9
SCHEMBL29441920 0.81 CA1 (0.44) FFAR1FFAR4MMP2MMP3MMP9
SCHEMBL28090593 0.81 CA1 (0.44) FFAR1FFAR4MMP2MMP3MMP9
SCHEMBL177562 0.80 FFAR1 (0.43) FFAR1FFAR4PPARAPPARDKMO
SCHEMBL27781799 0.80 AR (0.41) MMP2MMP3MMP9MMP14KCNH2
SCHEMBL3723019 0.79 SLC6A2 (0.41) SLC6A4SLC6A2SLC6A3
SCHEMBL30823228 0.79 SLC6A2 (0.41) SLC6A4SLC6A2SLC6A3
SCHEMBL27781798 0.78 VEGFA (0.41) FFAR4SLC6A4SLC6A2SLC6A3
SCHEMBL9467645 0.76 FFAR1 (0.45) FFAR1FFAR4KMOMMP2MMP3
SCHEMBL27781903 0.76 MRGPRX4 (0.43) FFAR4KCNH2MRGPRX4SCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101563089-A Boronic acids and esters as inhibitors of fatty amide hydrolase INFINITY DISCOVERY INC (US) 2009-10-21 CN disclosed