SCHEMBL3723019

SCHEMBL3723019

OB(O)Oc1ccc(F)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.41
SLC6A3 Q01959 3/20 0.41
SLC6A4 P31645 2/20 0.41
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
S1PR4 O95977 1/20 0.35
NISCH Q9Y2I1 1/20 0.34
CYP2D6 P10635 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
PKM P14618 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
SCN8A Q9UQD0 1/20 0.33
SCN10A Q9Y5Y9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30823228 1.00 SLC6A2 (0.41) SLC6A2SLC6A3SLC6A4NPC1RAB9A
SCHEMBL29191188 0.84 SLC6A4 (0.36) SLC6A2SLC6A4NISCH
SCHEMBL2268873 0.79 CES2 (0.39) ALDH1A1MEN1KMT2AL3MBTL1HPGD
SCHEMBL30506429 0.79 TTR (0.52) SLC6A2SLC6A3L3MBTL1HPGD
SCHEMBL1943056 0.79 TTR (0.52) SLC6A2SLC6A3L3MBTL1HPGD
SCHEMBL30523912 0.79 CES2 (0.39) ALDH1A1MEN1KMT2AL3MBTL1HPGD
SCHEMBL12538829 0.79 SLC6A2 (0.41) SLC6A2SLC6A3SLC6A4NPC1RAB9A
SCHEMBL27760244 0.79 FFAR1 (0.44) SLC6A2SLC6A3SLC6A4
SCHEMBL31114606 0.78 CA3 (0.46) NPC1RAB9AMEN1KMT2ACYP2D6
SCHEMBL3720785 0.76 MRGPRX4 (0.40) SLC6A2SLC6A3SLC6A4ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109422674-B Organic molecules, in particular for optoelectronic devices 三星显示有限公司 2024-03-22 CN disclosed
CN-102574788-A Indole derivatives as crac modulators HOFFMANN LA ROCHE 2012-07-11 CN disclosed
WO-2010117090-A1 NOVEL ISOQUINOLINYLOXYMETHYL HETEROARYL DERIVATIVES BANYU PHARMACEUTICAL CO.,LTD. (JP) 2010-10-14 WO disclosed
CN-100589803-C Aryl-pyridine derivatives HOFFMANN LA ROCHE 2010-02-17 CN disclosed
CN-1988905-A Aryl-pyridine derivatives HOFFMANN LA ROCHE (CH) 2007-06-27 CN disclosed