Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.52 |
| ▸ | MGLL | Q99685 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540283 | 0.93 | HRH3 (0.52) | HRH3MGLLHTTL3MBTL1KDM4E | |
| SCHEMBL27739853 | 0.91 | HRH3 (0.50) | HRH3L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL27739844 | 0.91 | HRH3 (0.50) | HRH3HTTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27739845 | 0.90 | HTT (0.54) | HRH3MGLLHTTL3MBTL1KDM4E | |
| SCHEMBL27739839 | 0.90 | HRH3 (0.54) | HRH3MGLLHTTL3MBTL1KDM4E | |
| SCHEMBL27760290 | 0.88 | HRH3 (0.52) | HRH3MGLLHTTL3MBTL1KDM4E | |
| SCHEMBL3541563 | 0.87 | HRH3 (0.52) | HRH3MGLLHTTL3MBTL1KDM4E | |
| SCHEMBL27739850 | 0.86 | HRH3 (0.51) | HRH3L3MBTL1L3MBTL3 | |
| SCHEMBL28775838 | 0.85 | L3MBTL1 (0.55) | HRH3HTTL3MBTL1KDM4EMEN1 | |
| SCHEMBL27739852 | 0.84 | HRH3 (0.52) | HRH3MGLLHTTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421235-A | 5-amido-2-amide indoles | HOFFMANN LA ROCHE (CH) | 2009-04-29 | — | — | CN | disclosed |