Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774548 | 1.00 | NR3C1 (0.58) | NR3C1KMT2AMEN1GAAMAPT | |
| SCHEMBL16774550 | 1.00 | NR3C1 (0.58) | NR3C1KMT2AMEN1GAAMAPT | |
| SCHEMBL27682561 | 0.96 | NR3C1 (0.59) | NR3C1KMT2AMEN1GAAMAPT | |
| SCHEMBL16774541 | 0.96 | NR3C1 (0.59) | NR3C1KMT2AMEN1GAAMAPT | |
| SCHEMBL16774542 | 0.96 | NR3C1 (0.59) | NR3C1KMT2AMEN1GAAMAPT | |
| SCHEMBL27682527 | 0.91 | CYP19A1 (0.48) | NR3C1KMT2AMEN1GAAMAPT | |
| SCHEMBL27682528 | 0.91 | CYP19A1 (0.48) | NR3C1KMT2AMEN1GAAMAPT | |
| SCHEMBL27701618 | 0.91 | CYP19A1 (0.48) | NR3C1KMT2AMEN1GAAMAPT | |
| SCHEMBL27682521 | 0.91 | NR3C1 (0.54) | NR3C1KMT2AMEN1GAAMAPT | |
| SCHEMBL27701629 | 0.91 | NR3C1 (0.55) | NR3C1KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100548979-C | A kind of method of synthetic 3-methyl amino indole compound | SHANGHAI INST ORGANIC CHEM (CN) | 2009-10-14 | — | — | CN | disclosed |