SCHEMBL27760643

SCHEMBL27760643

CCCc1cc(C(=O)O)oc1CCC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.60
KDM4E B2RXH2 2/20 0.60
POLB P06746 6/20 0.56
TDP1 Q9NUW8 3/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
ALDH1A1 P00352 4/20 0.49
APEX1 P27695 3/20 0.47
PTPN1 P18031 1/20 0.43
PTPN11 Q06124 1/20 0.43
KMT2A Q03164 3/20 0.40
ABCB11 O95342 1/20 0.39
PTGER4 P35408 2/20 0.38
DAO P14920 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
ACLY P53396 1/20 0.38
HSD17B10 Q99714 2/20 0.38
MEN1 O00255 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27760658 0.85 TDP1 (0.53) MAPTKDM4EPOLBTDP1L3MBTL1
SCHEMBL18062303 0.85 KDM4E (0.52) MAPTKDM4EPOLBTDP1L3MBTL1
SCHEMBL27760838 0.84 TDP1 (0.51) MAPTKDM4EPOLBTDP1L3MBTL1
SCHEMBL849075 0.83 MAPT (0.48) MAPTKDM4EPOLBTDP1L3MBTL1
SCHEMBL27782222 0.82 TDP1 (0.50) MAPTKDM4EPOLBTDP1L3MBTL1
SCHEMBL27760835 0.80 POLB (0.74) MAPTKDM4EPOLBTDP1L3MBTL1
SCHEMBL27760660 0.77 ALDH1A1 (0.56) MAPTKDM4EPOLBTDP1L3MBTL1
SCHEMBL19182828 0.72 TDP1 (0.54) MAPTKDM4EPOLBTDP1L3MBTL1
SCHEMBL12477776 0.70 KAT8 (0.44) MAPTPOLBTDP1L3MBTL1ALDH1A1
SCHEMBL28214993 0.70 KAT8 (0.44) MAPTPOLBTDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101560272-B Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO LTD 2011-04-13 CN disclosed
CN-101560273-B Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO LTD 2011-03-23 CN disclosed
CN-101560273-A Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO (CN) 2009-10-21 CN disclosed
CN-101560272-A Olefinic polymerization catalyst, preparation method and polymerization method YINGKOU XIANGYANG CATALYST CO (CN) 2009-10-21 CN disclosed