SCHEMBL27761012

SCHEMBL27761012

CC(=O)CC(=O)OC(Cl)C(C)=O

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
TDP1 Q9NUW8 1/20 0.32
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28119418 0.83 MGAM (0.55) MGAMGAASIMGAM2TDP1
SCHEMBL3279260 0.79 MGAM (0.50) MGAMGAASIMGAM2TDP1
SCHEMBL11278832 0.79 MGAM (0.50) MGAMGAASIMGAM2TDP1
SCHEMBL10652692 0.76 MGAM (0.46) MGAMGAASIMGAM2TDP1
SCHEMBL18135603 0.74 MGAM (0.50) MGAMGAASIMGAM2TDP1
SCHEMBL28188671 0.74 MGAM (0.44) MGAMGAASIMGAM2TDP1
SCHEMBL27553631 0.74 MGAM (0.44) MGAMGAASIMGAM2
SCHEMBL5615473 0.73 MGAM (0.55) MGAMGAASIMGAM2TDP1
SCHEMBL29438274 0.73 MGAM (0.55) MGAMGAASIMGAM2TDP1
SCHEMBL182320 0.73 MGAM (0.55) MGAMGAASIMGAM2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101565409-B Piperazidine or homopiperazine oxalyl hydrazine class compound, preparation and use thereof SHENZHEN XIANGYA BIOLOGY MEDICAMENT ACADEMY 2011-09-07 CN claimed
CN-101565409-A Piperazidine or homopiperazine oxalyl hydrazine class compound, preparation and use thereof SHENZHEN XIANGYA BIOLOGY MEDIC (CN) 2009-10-28 CN claimed
CN-101565409-B Piperazidine or homopiperazine oxalyl hydrazine class compound, preparation and use thereof SHENZHEN XIANGYA BIOLOGY MEDICAMENT ACADEMY 2011-09-07 CN disclosed
CN-101565409-A Piperazidine or homopiperazine oxalyl hydrazine class compound, preparation and use thereof SHENZHEN XIANGYA BIOLOGY MEDIC (CN) 2009-10-28 CN disclosed