Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278832 | 1.00 | MGAM (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL9065292 | 0.87 | MGAM (0.38) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL28119418 | 0.85 | MGAM (0.55) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL9065300 | 0.81 | LDHA (0.36) | TSHRALDH1A1TDP1FAAHMAPT | |
| SCHEMBL6837511 | 0.80 | MGAM (0.55) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL29438274 | 0.80 | MGAM (0.55) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL182320 | 0.80 | MGAM (0.55) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL8751786 | 0.80 | MGAM (0.55) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27761012 | 0.79 | MGAM (0.48) | MGAMGAASIMGAM2TDP1 | |
| SCHEMBL20481946 | 0.78 | MGAM (0.52) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408827-A1 | A NEW INTERMEDIATE FOR PREPARATION OF OXAZOLE COMPOUNDS | DSM IP Assets B.V. (NL) | 2024-08-07 | — | — | EP | disclosed |
| EP-4408828-A1 | A PROCESS FOR PREPARATION OF OXAZOLE COMPOUNDS | DSM IP Assets B.V. (NL) | 2024-08-07 | — | — | EP | disclosed |
| CN-117209418-A | Preparation and purification method of high-purity nicardipine hydrochloride | 华仁医学研究(安徽)有限公司 | 2023-12-12 | — | — | CN | disclosed |
| EP-4192820-A1 | A PROCESS FOR PREPARATION OF OXAZOLE COMPOUNDS | DSM IP Assets B.V. (NL) | 2023-06-14 | — | — | EP | disclosed |
| WO-2023052104-A1 | A PROCESS FOR PREPARATION OF OXAZOLE COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2023-04-06 | — | — | WO | disclosed |
| WO-2023052103-A1 | A NEW INTERMEDIATE FOR PREPARATION OF OXAZOLE COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2023-04-06 | — | — | WO | disclosed |
| WO-2022053318-A1 | A PROCESS FOR PRODUCING OXAZOLE COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2022-03-17 | — | — | WO | disclosed |
| WO-2022028941-A1 | A PROCESS FOR PREPARATION OF OXAZOLE COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2022-02-10 | — | — | WO | disclosed |
| CN-107879935-A | Method for synthesizing vinyl carboxylate | 王建华 | 2018-04-06 | — | — | CN | disclosed |
| CN-106456609-A | Substituted indazole compounds as irak4 inhibitors | 奥瑞基尼探索技术有限公司 | 2017-02-22 | — | — | CN | disclosed |
| US-7696210-B2 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2010-04-13 | — | — | US | disclosed |
| EP-1758895-A1 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2007-03-07 | — | — | EP | disclosed |
| CN-1874989-A | Process for preparing -or (R) -4-halo-3-hydroxybutyric acid esters | LONZA AG (CH) | 2006-12-06 | — | — | CN | disclosed |
| US-20060019965-A1 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2006009734-A1 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | WYETH (US) | 2006-01-26 | — | — | WO | disclosed |
| CN-1578660-A | Lactam-containing compounds and derivatives thereof as factor xa inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2005-02-09 | — | — | CN | disclosed |
| EP-0216542-B1 | DIHYDROPYRIDINE DERIVATIVES | THE GREEN CROSS CORPORATION (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4849429-A | CARDIOVASCULAR, HYPOTENSIVE, ENZYME INHIBITOR | THE GREEN CROSS CORPORATION (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0063747-B1 | 2-SUBSTITUTED OR UNSUBSTITUTED AMINOCARBONYLOXYALKYL-1,4-DIHYDROPYRIDINES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-12-09 | — | — | EP | disclosed |
| EP-0216542-A1 | Dihydropyridine derivatives | THE GREEN CROSS CORPORATION (JP) | 1987-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019965-A1 | Gonadotropin releasing hormone receptor antagonists | GNRHR, GHRHR, LHCGR | MGAM 2872/4885GAA 1721/4885SI 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.