Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356036 | 0.96 | HTT (0.60) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL27782813 | 0.83 | SMN1; SMN2 (0.76) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL27782809 | 0.83 | POLB (0.61) | HTTSMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL17956821 | 0.82 | HTT (0.60) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4356054 | 0.79 | MAPK1 (0.70) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4350067 | 0.79 | SMN1; SMN2 (0.70) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4357568 | 0.79 | EPHX1 (0.58) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4350868 | 0.76 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL15894091 | 0.75 | LMNA (0.83) | HTTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL4341984 | 0.75 | GAA (0.65) | HTTSMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100546977-C | Suppress the new compound and the application thereof of rotamase | JERINI AG (DE) | 2009-10-07 | — | — | CN | claimed |