Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776048 | 0.67 | KDM4E (0.67) | KDM4ESMN1; SMN2TP53LMNAHTT | |
| SCHEMBL1181563 | 0.66 | KDM4E (0.88) | KDM4ESMN1; SMN2TP53LMNAHTT | |
| SCHEMBL9170911 | 0.65 | KDM4E (0.48) | KDM4ESMN1; SMN2TP53LMNAHTT | |
| SCHEMBL3036765 | 0.64 | KDM4E (0.82) | KDM4ESMN1; SMN2TP53LMNAHTT | |
| SCHEMBL14970145 | 0.64 | KDM4E (0.61) | KDM4ESMN1; SMN2TP53LMNAHTT | |
| SCHEMBL6535045 | 0.63 | KDM4E (0.67) | KDM4ESMN1; SMN2TP53LMNAHTT | |
| Terpyridine SCHEMBL30610403 | 0.62 | KDM4E (0.90) | KDM4ESMN1; SMN2TP53LMNAHTT | |
| SCHEMBL24708127 | 0.62 | ABL1 (0.38) | SYK | |
| Terpyridine SCHEMBL57442 | 0.62 | KDM4E (1.00) | KDM4ESMN1; SMN2TP53LMNAHTT | |
| Dipyridyl SCHEMBL5787557 | 0.62 | KDM4E (0.78) | KDM4ESMN1; SMN2TP53LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101417995-A | Phenoxy pyrimidine derivates and its production and use | YIJUN CHEN (CN) | 2009-04-29 | — | — | CN | disclosed |