Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 6/20 | 0.41 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761682 | 0.78 | KDM4E (0.41) | HSP90AA1NPC1RAB9A | |
| SCHEMBL18615439 | 0.73 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1PTK2ABL1PRKCA | |
| Hydrochloric Acid SCHEMBL20357284 | 0.72 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1PTK2ABL1PRKCA | |
| Hydrochloric Acid SCHEMBL20357283 | 0.72 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1PTK2ABL1PRKCA | |
| SCHEMBL18615680 | 0.71 | CKS1B (0.46) | ABL1RAB9ABCRDUSP10SRC | |
| SCHEMBL20357315 | 0.68 | ABL1 (0.43) | HSP90AA1HSP90AB1PTK2ABL1PRKCA | |
| SCHEMBL28739390 | 0.68 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1PTK2ABL1PRKCA | |
| SCHEMBL10917422 | 0.68 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PTK2ABL1PRKCA | |
| SCHEMBL10817967 | 0.67 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1PTK2ABL1PRKCA | |
| SCHEMBL27991965 | 0.67 | ABL1 (0.52) | HSP90AA1HSP90AB1PTK2ABL1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101417995-A | Phenoxy pyrimidine derivates and its production and use | YIJUN CHEN (CN) | 2009-04-29 | — | — | CN | disclosed |