Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762739 | 0.91 | TSHR (0.45) | TSHRALDH1A1HPGDKDM4ETDP1 | |
| Anisole SCHEMBL27762741 | 0.81 | DAPK1 (0.43) | TSHRALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL1306717 | 0.80 | MAPT (0.53) | ALDH1A1HPGDKDM4EDAPK1PIM3 | |
| SCHEMBL1306720 | 0.80 | MAPT (0.53) | ALDH1A1HPGDKDM4EDAPK1PIM3 | |
| SCHEMBL1306788 | 0.78 | PTPN1 (0.48) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL1306787 | 0.78 | PTPN1 (0.48) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL3821011 | 0.76 | TSHR (0.43) | TSHRALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL3816994 | 0.76 | KDM4E (0.45) | TSHRALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL1305765 | 0.74 | MEN1 (0.45) | TSHRALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL1305762 | 0.74 | MEN1 (0.45) | TSHRALDH1A1HPGDKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101573327-A | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RES INST CHEM TECH (KR) | 2009-11-04 | — | — | CN | disclosed |