Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAPK1 | P53355 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306720 | 0.90 | MAPT (0.53) | DAPK1PIM3HPGDALDH1A1KDM4E | |
| SCHEMBL1306717 | 0.90 | MAPT (0.53) | DAPK1PIM3HPGDALDH1A1KDM4E | |
| Fluorobenzene SCHEMBL27762740 | 0.90 | DAPK1 (0.44) | DAPK1PIM3HPGDALDH1A1KDM4E | |
| SCHEMBL1306788 | 0.87 | PTPN1 (0.48) | HPGDALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL1306787 | 0.87 | PTPN1 (0.48) | HPGDALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL1307248 | 0.85 | LMNA (0.52) | DAPK1PIM3HPGDALDH1A1KDM4E | |
| SCHEMBL1307250 | 0.85 | LMNA (0.52) | DAPK1PIM3HPGDALDH1A1KDM4E | |
| SCHEMBL1307060 | 0.81 | HDAC1 (0.54) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL1307057 | 0.81 | HDAC1 (0.54) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL27762736 | 0.81 | TSHR (0.43) | DAPK1PIM3HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101573327-A | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RES INST CHEM TECH (KR) | 2009-11-04 | — | — | CN | disclosed |