SCHEMBL2776337

SCHEMBL2776337

CN(C)c1ccc(C=Cc2ccccc2N(C)C)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.67
RELA Q04206 1/20 0.66
MEN1 O00255 7/20 0.52
KMT2A Q03164 7/20 0.52
MAPT P10636 5/20 0.52
RAB9A P51151 5/20 0.52
NPC1 O15118 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
CASP1 P29466 2/20 0.52
HBB P68871 2/20 0.52
ALOX15 P16050 1/20 0.52
SNCA P37840 2/20 0.51
RAD52 P43351 2/20 0.50
MAT2A P31153 1/20 0.50
KCNH2 Q12809 1/20 0.50
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
HTT P42858 3/20 0.49
NPSR1 Q6W5P4 3/20 0.49
ALDH1A1 P00352 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2776332 1.00 APP (0.67) APPRELAMEN1KMT2AMAPT
SCHEMBL2845206 0.86 RELA (0.55) APPRELASNCAMAOB
SCHEMBL2845201 0.86 RELA (0.55) APPRELASNCAMAOB
SCHEMBL29808641 0.85 RELA (0.53) APPRELASNCAMAOB
SCHEMBL29523356 0.84 GSK3B (0.44) APPRELAMAPTSMN1; SMN2ALDH1A1
SCHEMBL14895393 0.81 APP (0.67) APPRELAMEN1KMT2AMAPT
SCHEMBL2775540 0.81 APP (0.46) APPRELAMAPTRAB9ANPC1
SCHEMBL2775543 0.81 APP (0.46) APPRELAMAPTRAB9ANPC1
SCHEMBL4072573 0.80 MAPT (0.55) APPRELAMEN1KMT2AMAPT
SCHEMBL2487914 0.80 APP (0.65) APPRELAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026088-B1 PHOTORESIST COMPOSITIONS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-11-23 EP claimed
US-4349619-A CONTAINING ANTIHALATION AGENTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-14 US claimed
EP-0026088-A2 Photoresist compositions JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-04-01 EP claimed
US-20100302927-A1 OPTICAL DATA STORAGE MEDIUM AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2010-12-02 US disclosed
EP-0026088-B1 PHOTORESIST COMPOSITIONS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-11-23 EP disclosed
US-4349619-A CONTAINING ANTIHALATION AGENTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-14 US disclosed
EP-0026088-A2 Photoresist compositions JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-04-01 EP disclosed