Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605345 | 0.83 | CA2 (0.37) | USP2TSHRCA2MAPK1CA1 | |
| SCHEMBL27559021 | 0.83 | CA2 (0.37) | USP2TSHRCA2MAPK1CA1 | |
| SCHEMBL27671851 | 0.83 | CA2 (0.37) | USP2TSHRCA2MAPK1CA1 | |
| SCHEMBL27842178 | 0.78 | CA1 (0.38) | USP2TSHRCA2CA1LMNA | |
| SCHEMBL7356322 | 0.74 | — | — | |
| SCHEMBL27616177 | 0.73 | CA2 (0.32) | CA2MAPK1CA1 | |
| SCHEMBL27785585 | 0.73 | CA2 (0.32) | CA2MAPK1CA1 | |
| SCHEMBL27577240 | 0.73 | CA2 (0.32) | CA2MAPK1CA1 | |
| SCHEMBL9389418 | 0.73 | TSHR (0.42) | USP2TSHRCA2MAPK1CA1 | |
| SCHEMBL10634919 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101573335-A | Kinase inhibitors | TAKEDA SAN DIEGO INC (JP) | 2009-11-04 | — | — | CN | disclosed |