SCHEMBL27764413

SCHEMBL27764413

O=C(Nc1ccc(C(F)(F)F)cc1)NC1CCN(C(=O)c2ccccc2N2CCOCC2)CC1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27786077 0.87 EPHX2 (0.57) EPHX2
SCHEMBL3961426 0.85 EPHX2 (0.69) EPHX2
SCHEMBL4997912 0.82 EPHX2 (0.76) EPHX2
SCHEMBL4010073 0.79 EPHX2 (0.67) EPHX2
SCHEMBL4012519 0.79 TRPV1 (0.64) EPHX2
SCHEMBL4016622 0.78 EPHX2 (0.72) EPHX2
SCHEMBL17130361 0.78 EPHX2 (1.00) EPHX2
SCHEMBL3958181 0.77 EPHX2 (0.74) EPHX2
SCHEMBL17130381 0.77 EPHX2 (1.00) EPHX2
SCHEMBL3346367 0.76 EPHX2 (0.79) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101535259-A Phenylurea compounds as soluble epoxide hydrolase inhibitors ARETE THERAPEUTICS INC (US) 2009-09-16 — — CN claimed
CN-101535259-A Phenylurea compounds as soluble epoxide hydrolase inhibitors ARETE THERAPEUTICS INC (US) 2009-09-16 — — CN disclosed
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