Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 18/20 | 0.72 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.65 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010073 | 0.94 | EPHX2 (0.67) | EPHX2TRPV1USP30 | |
| SCHEMBL3961426 | 0.85 | EPHX2 (0.69) | EPHX2 | |
| SCHEMBL3346367 | 0.84 | EPHX2 (0.79) | EPHX2 | |
| SCHEMBL4011037 | 0.84 | EPHX2 (0.79) | EPHX2 | |
| SCHEMBL2716707 | 0.84 | EPHX2 (1.00) | EPHX2USP30 | |
| SCHEMBL2752048 | 0.83 | EPHX2 (0.71) | EPHX2 | |
| SCHEMBL4012519 | 0.83 | TRPV1 (0.64) | EPHX2TRPV1USP30 | |
| SCHEMBL3353004 | 0.83 | CA12 (0.72) | EPHX2TRPV1 | |
| SCHEMBL3347934 | 0.83 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL3352294 | 0.83 | EPHX2 (0.73) | EPHX2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086426-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR THE TREATMENT OF ENDOTHELIAL DYSFUNCTION | ARETE THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |