Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 3/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 6/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 6/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805877 | 0.85 | RXRA (0.43) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL31642472 | 0.85 | RXRA (0.43) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL31628652 | 0.83 | RXRA (0.42) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL29416187 | 0.83 | RXRA (0.42) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL1193030 | 0.83 | RXRA (0.42) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL156398 | 0.83 | RXRA (0.42) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL4572292 | 0.83 | CYP4F2 (0.46) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL168052 | 0.83 | DDB1 (0.51) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL1141884 | 0.83 | RXRA (0.45) | RXRARXRBRXRGALDH1A1LMNA | |
| SCHEMBL476884 | 0.83 | RXRA (0.42) | RXRARXRBRXRGALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101460477-A | Novel indazole derivative having spiro ring structure in side chain | UBE INDUSTRIES (JP) | 2009-06-17 | — | — | CN | disclosed |