Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 3/20 | 0.42 |
| ▸ | FABP3 | P05413 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367040 | 0.89 | HSD17B10 (0.61) | GAAHSD17B10ALDH1A1PGRPTGS1 | |
| Ammonia Solution, Strong SCHEMBL11430486 | 0.87 | HSD17B10 (0.59) | GAAHSD17B10ALDH1A1PGRPTGS1 | |
| SCHEMBL18817858 | 0.86 | HSD17B10 (0.53) | GAAHSD17B10ALDH1A1PGRPTGS1 | |
| SCHEMBL27807134 | 0.84 | HSD17B10 (0.51) | GAAHSD17B10ALDH1A1PGRPTGS1 | |
| SCHEMBL2395666 | 0.84 | HSD17B10 (0.51) | GAAHSD17B10ALDH1A1PGRPTGS1 | |
| SCHEMBL11152562 | 0.83 | ALDH1A1 (0.54) | GAAHSD17B10ALDH1A1PGRPTGS1 | |
| SCHEMBL1394636 | 0.83 | HSD17B10 (0.50) | GAAHSD17B10ALDH1A1PGRPTGS1 | |
| SCHEMBL28689978 | 0.83 | ALDH1A1 (0.54) | GAAHSD17B10ALDH1A1PGRPTGS1 | |
| Acrylic Acid SCHEMBL28166549 | 0.82 | ALDH1A1 (0.50) | GAAHSD17B10ALDH1A1PGRPTGS1 | |
| Butane SCHEMBL8966575 | 0.81 | ALDH1A1 (0.57) | GAAHSD17B10ALDH1A1PGRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109662964-A | For improving the method and composition of cognitive function | 约翰斯.霍普金斯大学 | 2019-04-23 | — | — | CN | disclosed |
| CN-105143177-B | The manufacturing method of xylylene diisocyanate and the manufacturing device of xylylene diisocyanate | 三井化学株式会社 | 2018-07-10 | — | — | CN | disclosed |
| CN-105377808-B | Method for producing trans-bis (aminomethyl) cyclohexane and method for producing bis (isocyanatomethyl) cyclohexane | 三井化学株式会社 | 2018-05-29 | — | — | CN | disclosed |
| CN-105142623-A | Methods and compositions for improving cognitive function | AGENEBIO INC | 2015-12-09 | — | — | CN | disclosed |
| CN-102905532-A | Methods and compositions for improving cognitive function | UNIV JOHNS HOPKINS | 2013-01-30 | — | — | CN | disclosed |
| CN-101563083-A | Combinations containing a 4-acylaminopyridine derivative | BRAINCELLS INC (US) | 2009-10-21 | — | — | CN | disclosed |