Phosphoric Acid

Phosphoric Acid

SCHEMBL27765779

O=C(O)C(O)CO.O=P(O)(O)O.OO

nearest known ligand 0.78

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.78
PGK1 P00558 1/20 0.50
PGK2 P07205 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.43
TET2 Q6N021 6/20 0.40
KDM4A O75164 2/20 0.40
KDM4C Q9H3R0 2/20 0.40
KDM2A Q9Y2K7 2/20 0.40
TET3 O43151 2/20 0.40
TET1 Q8NFU7 1/20 0.37
PDE4A P27815 1/20 0.37
PGD P52209 1/20 0.37
GPR84 Q9NQS5 2/20 0.34
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL42321 1.00 OR51E2 (0.78) OR51E2PGK1PGK2SMN1; SMN2TET2
Phosphoric Acid SCHEMBL1462678 1.00 OR51E2 (0.78) OR51E2PGK1PGK2SMN1; SMN2TET2
SCHEMBL29597490 0.88
SCHEMBL1765577 0.88 OR51E2 (1.00) OR51E2PGK1PGK2SMN1; SMN2TET2
Water SCHEMBL10757023 0.88
SCHEMBL29278852 0.88 OR51E2 (1.00) OR51E2PGK1PGK2SMN1; SMN2TET2
SCHEMBL2905876 0.88
SCHEMBL38462 0.88
Water SCHEMBL21753470 0.88
SCHEMBL584528 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101620098-A Inorganic phosphorus (phosphate radical) diagnosis/determination kit and method for determining inorganic phosphorus (phosphate radical) concentration-834 SUZHOU ANJ BIOTECH CO LTD 2010-01-06 CN claimed
CN-101464390-A Monoamine oxidase diagnostic reagent kit and method for measuring active concentration of monoamine oxidase SUZHOU ANJ BIOTECH CO LTD (CN) 2009-06-24 CN claimed
CN-101464331-A Selenium diagnosis/measuring reagent kit and method for measuring selenium concentration SUZHOU ANJ BIOTECH CO LTD (CN) 2009-06-24 CN claimed
CN-101620098-A Inorganic phosphorus (phosphate radical) diagnosis/determination kit and method for determining inorganic phosphorus (phosphate radical) concentration-834 SUZHOU ANJ BIOTECH CO LTD 2010-01-06 CN disclosed
CN-101464390-A Monoamine oxidase diagnostic reagent kit and method for measuring active concentration of monoamine oxidase SUZHOU ANJ BIOTECH CO LTD (CN) 2009-06-24 CN disclosed
CN-101464331-A Selenium diagnosis/measuring reagent kit and method for measuring selenium concentration SUZHOU ANJ BIOTECH CO LTD (CN) 2009-06-24 CN disclosed