Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753174 | 0.89 | MAPT (0.66) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL27744844 | 0.86 | MAPT (0.51) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL4169112 | 0.84 | MAPT (0.55) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL4169690 | 0.83 | MAPT (0.56) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL27765794 | 0.82 | AOC3 (0.40) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL4164415 | 0.81 | MAPT (0.54) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL4167589 | 0.81 | GRM1 (0.61) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL4172768 | 0.80 | MAPT (0.54) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL4171566 | 0.79 | MAPT (0.53) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL1753279 | 0.79 | MAPT (0.80) | MAPTSMN1; SMN2HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101454327-A | Azolopyrimidines as inhibitors of cannabinoid 1 activity | IRM LLC (BM) | 2009-06-10 | — | — | CN | claimed |
| CN-101454327-A | Azolopyrimidines as inhibitors of cannabinoid 1 activity | IRM LLC (BM) | 2009-06-10 | — | — | CN | disclosed |