Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765795 | 0.86 | MAPT (0.53) | MAPTSMN1; SMN2TP53HPGDALDH1A1 | |
| SCHEMBL4157160 | 0.84 | MAPT (0.54) | MAPTSMN1; SMN2TP53HPGDALDH1A1 | |
| SCHEMBL28776509 | 0.83 | XDH (0.38) | MAPTSMN1; SMN2TP53HPGDALDH1A1 | |
| SCHEMBL4164601 | 0.83 | GRM1 (0.67) | MAPTSMN1; SMN2TP53HPGDALDH1A1 | |
| SCHEMBL4163363 | 0.82 | MAPT (0.53) | MAPTSMN1; SMN2TP53HPGDALDH1A1 | |
| SCHEMBL4164801 | 0.82 | GRM1 (0.59) | MAPTSMN1; SMN2TP53HPGDALDH1A1 | |
| SCHEMBL1753270 | 0.80 | GRM1 (0.66) | MAPTSMN1; SMN2TP53HPGDALDH1A1 | |
| SCHEMBL4166802 | 0.80 | MAPT (0.53) | MAPTSMN1; SMN2TP53HPGDALDH1A1 | |
| SCHEMBL4180742 | 0.80 | GRM1 (0.56) | MAPTSMN1; SMN2TP53HPGDALDH1A1 | |
| SCHEMBL4172288 | 0.80 | MAPT (0.52) | MAPTSMN1; SMN2TP53HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101454327-A | Azolopyrimidines as inhibitors of cannabinoid 1 activity | IRM LLC (BM) | 2009-06-10 | — | — | CN | claimed |
| CN-101454327-A | Azolopyrimidines as inhibitors of cannabinoid 1 activity | IRM LLC (BM) | 2009-06-10 | — | — | CN | disclosed |