Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 7/20 | 0.47 |
| ▸ | ADCY6 | O43306 | 3/20 | 0.47 |
| ▸ | ADCY3 | O60266 | 3/20 | 0.47 |
| ▸ | ADCY9 | O60503 | 3/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.47 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.47 |
| ▸ | ADCY7 | P51828 | 3/20 | 0.47 |
| ▸ | ADCY2 | Q08462 | 3/20 | 0.47 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.47 |
| ▸ | ADCY4 | Q8NFM4 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2658999 | 0.87 | GCGR (0.46) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2656724 | 0.84 | GCGR (0.46) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2656926 | 0.83 | KMT2A (0.53) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2657103 | 0.82 | GAA (0.48) | KMT2A | |
| SCHEMBL28064474 | 0.80 | PPARG (0.41) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2659405 | 0.79 | KMT2A (0.53) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2662588 | 0.77 | PPARG (0.48) | KMT2A | |
| SCHEMBL28064556 | 0.77 | MAPT (0.39) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2669752 | 0.77 | GCGR (0.46) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL11999239 | 0.75 | GCGR (0.47) | GCGRADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101610995-A | Novel glucagon receptor antagonists | METABASIS THERAPEUTICS INC (US) | 2009-12-23 | — | — | CN | disclosed |