Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.36 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28064556 | 0.97 | MAPT (0.39) | PPARGPPARAALDH1A1KDM4EKMT2A | |
| SCHEMBL28780838 | 0.90 | ALDH1A1 (0.41) | PPARGPPARAALDH1A1KDM4EKMT2A | |
| SCHEMBL2658999 | 0.80 | GCGR (0.46) | ALDH1A1KDM4EKMT2AMEN1HRH3 | |
| SCHEMBL27766006 | 0.80 | GCGR (0.47) | KMT2AGCGRADCY6ADCY3ADCY9 | |
| SCHEMBL2656926 | 0.78 | KMT2A (0.53) | PPARGPPARAALDH1A1KDM4EKMT2A | |
| SCHEMBL2656724 | 0.77 | GCGR (0.46) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2657103 | 0.77 | GAA (0.48) | PPARGPPARAALDH1A1KDM4EKMT2A | |
| SCHEMBL2659405 | 0.74 | KMT2A (0.53) | PPARGPPARAALDH1A1KDM4EKMT2A | |
| SCHEMBL2662588 | 0.73 | PPARG (0.48) | PPARGPPARAALDH1A1KDM4EKMT2A | |
| SCHEMBL28064381 | 0.72 | CSF1R (0.49) | ALDH1A1KDM4EKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566265-A | Antagonists of the glucagon receptor | METABASIS THERAPEUTICS INC | 2016-05-11 | — | — | CN | disclosed |