Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27973861 | 0.86 | MAPK1 (0.43) | SMN1; SMN2USP2ALDH1A1KMT2ARAB9A | |
| SCHEMBL27974043 | 0.79 | RECQL (0.47) | MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL12616867 | 0.72 | GRM2 (0.40) | DDB1CRBNPOLBSMN1; SMN2MAPT | |
| SCHEMBL8893179 | 0.71 | MAPT (0.48) | POLBSMN1; SMN2MAPTALDH1A1MTNR1A | |
| SCHEMBL10752342 | 0.71 | DDB1 (0.44) | DDB1CRBNPOLBMT-CO2ALOX5 | |
| SCHEMBL14943747 | 0.69 | USP30 (0.51) | DDB1CRBNPOLBMT-CO2ALOX5 | |
| SCHEMBL13803643 | 0.69 | ALDH1A1 (0.58) | SMN1; SMN2MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL1027868 | 0.69 | KMT2A (0.40) | POLBSMN1; SMN2MAPTUSP2ALDH1A1 | |
| SCHEMBL12635405 | 0.68 | GRM2 (0.51) | — | |
| SCHEMBL1243655 | 0.67 | GRM5 (0.54) | DDB1CRBNPOLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101475523-A | 3-acyl pyrroline-2-ketoxime ether compound, and preparation and use thereof | UNIV NANJING AGRICULTURAL (CN) | 2009-07-08 | — | — | CN | disclosed |