Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 9/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788873 | 0.86 | PARP1 (0.43) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27767442 | 0.86 | PARP1 (0.43) | CDC7BRD4MAP4K4ALDH1A1HPGD | |
| SCHEMBL27767416 | 0.86 | CDC7 (0.52) | CDC7BRD4CHEK1KCNH2CCNA2 | |
| SCHEMBL27788862 | 0.85 | BRD4 (0.56) | CDC7BRD4ALDH1A1CCNA2CDK2 | |
| SCHEMBL27788983 | 0.85 | PARP1 (0.44) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27767529 | 0.85 | CDC7 (0.52) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27767430 | 0.83 | PARP1 (0.46) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27767459 | 0.82 | CDC7 (0.42) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27788866 | 0.82 | CDC7 (0.55) | CDC7BRD4ALDH1A1HPGDPARP1 | |
| SCHEMBL27788869 | 0.82 | CDC7 (0.55) | CDC7BRD4PARP1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622229-B | Pyrrole derivatives having ureido and aminocarbonyl groups as substituents | SANTEN PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | claimed |
| CN-101622229-A | Novel pyrrole derivatives having ureido group and aminocarbonyl group as substituents | SANTEN PHARMACEUTICAL CO LTD | 2010-01-06 | — | — | CN | claimed |
| CN-101622229-B | Pyrrole derivatives having ureido and aminocarbonyl groups as substituents | SANTEN PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | disclosed |
| CN-101622229-A | Novel pyrrole derivatives having ureido group and aminocarbonyl group as substituents | SANTEN PHARMACEUTICAL CO LTD | 2010-01-06 | — | — | CN | disclosed |