Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 14/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788869 | 0.88 | CDC7 (0.55) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27788873 | 0.83 | PARP1 (0.43) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27767442 | 0.83 | PARP1 (0.43) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27788862 | 0.82 | BRD4 (0.56) | CDC7BRD4CCNA2CDK2CCNA1 | |
| SCHEMBL27767529 | 0.82 | CDC7 (0.52) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27767415 | 0.82 | CDC7 (0.52) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27788983 | 0.82 | PARP1 (0.44) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27767430 | 0.80 | PARP1 (0.46) | CDC7BRD4PARP1CCNA2CDK2 | |
| SCHEMBL27788866 | 0.79 | CDC7 (0.55) | CDC7BRD4PARP1IKBKB | |
| SCHEMBL27767429 | 0.78 | CDC7 (0.45) | CDC7BRD4PARP1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622229-B | Pyrrole derivatives having ureido and aminocarbonyl groups as substituents | SANTEN PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | claimed |
| CN-101622229-A | Novel pyrrole derivatives having ureido group and aminocarbonyl group as substituents | SANTEN PHARMACEUTICAL CO LTD | 2010-01-06 | — | — | CN | claimed |
| CN-101622229-B | Pyrrole derivatives having ureido and aminocarbonyl groups as substituents | SANTEN PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | disclosed |
| CN-101622229-A | Novel pyrrole derivatives having ureido group and aminocarbonyl group as substituents | SANTEN PHARMACEUTICAL CO LTD | 2010-01-06 | — | — | CN | disclosed |