Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27767685 | 0.89 | CYP4F2 (0.43) | CYP4F2CYP4A11CCR5HSP90AA1IGF1R | |
| SCHEMBL27767711 | 0.88 | MAPT (0.42) | CYP4F2CYP4A11ALOX15SLC5A1SLC5A2 | |
| SCHEMBL27746650 | 0.88 | AKT1 (0.44) | CYP4F2CYP4A11HSD17B10 | |
| SCHEMBL27746654 | 0.86 | SLC5A1 (0.41) | CYP4F2CYP4A11L3MBTL1SLC5A1SLC5A2 | |
| SCHEMBL27767698 | 0.85 | NPSR1 (0.44) | BACE1CCR5PTPN5NPSR1VKORC1 | |
| SCHEMBL28781280 | 0.82 | PTGS1 (0.43) | BACE1CCR5PTPN5NPSR1VKORC1 | |
| SCHEMBL27746708 | 0.82 | CYP4F2 (0.38) | CYP4F2CYP4A11CCR5SLC5A1SLC5A2 | |
| SCHEMBL28776651 | 0.79 | BACE1 (0.47) | BACE1NPSR1MAPTTSHR | |
| SCHEMBL27746660 | 0.77 | THRA (0.48) | BACE1PTPN5NPSR1NFKB1NFKB2 | |
| SCHEMBL28776648 | 0.76 | AKT1 (0.47) | CYP4F2CYP4A11MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472937-A | Benzylphenylglucopyranoside Derivatives | DAIICHI SANKYO CO LTD (JP) | 2009-07-01 | — | — | CN | disclosed |