Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.48 |
| ▸ | THRB | P10828 | 8/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27746660 | 0.89 | THRA (0.48) | THRATHRBCYP3A4KDM4EKMT2A | |
| SCHEMBL27767713 | 0.89 | THRA (0.50) | THRATHRBCYP3A4LMNACYP4F2 | |
| SCHEMBL4797378 | 0.88 | THRA (0.49) | THRATHRBCYP3A4LMNACYP4F2 | |
| SCHEMBL27746659 | 0.86 | THRA (0.48) | THRATHRBCYP3A4LMNAPOLB | |
| SCHEMBL27746702 | 0.86 | THRA (0.48) | THRATHRBCYP3A4LMNACYP4F2 | |
| SCHEMBL27767721 | 0.84 | THRA (0.49) | THRATHRBKDM4EPOLBKMT2A | |
| SCHEMBL6724702 | 0.82 | SLC5A1 (0.47) | THRATHRBLMNAKDM4EKMT2A | |
| SCHEMBL27746689 | 0.82 | THRA (0.44) | THRATHRBCYP3A4LMNAKDM4E | |
| SCHEMBL27767700 | 0.82 | THRA (0.44) | THRATHRBCYP3A4KDM4EGLA | |
| SCHEMBL27746667 | 0.80 | HTT (0.41) | THRATHRBLMNACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472937-A | Benzylphenylglucopyranoside Derivatives | DAIICHI SANKYO CO LTD (JP) | 2009-07-01 | — | — | CN | disclosed |