Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775932 | 0.86 | KMT2A (0.46) | SMN1; SMN2ALOX15KMT2ATP53MAPT | |
| Hydrochloric Acid SCHEMBL2777358 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2ALOX15KMT2ATP53MAPT | |
| SCHEMBL6524551 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2ALOX15KMT2ATP53MAPT | |
| SCHEMBL5098870 | 0.79 | HRH1 (0.49) | CCR1 | |
| SCHEMBL7083748 | 0.79 | HRH1 (0.49) | CCR1 | |
| SCHEMBL2775706 | 0.79 | CCR1 (0.51) | KMT2AACACBCCR1HRH3LMNA | |
| SCHEMBL2775119 | 0.78 | CCR1 (0.57) | CCR1 | |
| SCHEMBL2775803 | 0.78 | CCR1 (0.55) | KMT2ACCR1HRH3LMNAATM | |
| SCHEMBL2780495 | 0.78 | CCR1 (0.55) | KMT2ACCR1HRH3LMNAATM | |
| SCHEMBL2774368 | 0.78 | EPHX2 (0.50) | MAPTACACBCCR1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |