Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | GHSR | Q92847 | 9/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.34 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27789521 | 0.89 | AOC3 (0.44) | AOC3CCNT1CDK9GHSREPHA2 | |
| Tert-Butyl Formate SCHEMBL27973827 | 0.87 | AOC3 (0.47) | AOC3CCNT1CDK9EPHA2KDR | |
| Tert-Butyl Formate SCHEMBL28784623 | 0.86 | AOC3 (0.38) | AOC3CCNT1CDK9EPHA2KDR | |
| Tert-Butyl Formate SCHEMBL27789576 | 0.86 | AOC3 (0.40) | AOC3EPHA2KDREPHB4BAZ2A | |
| Tert-Butyl Formate SCHEMBL27768398 | 0.84 | GPR119 (0.44) | AOC3EPHA2KDREPHB4BAZ2A | |
| Tert-Butyl Formate SCHEMBL27768084 | 0.84 | AOC3 (0.42) | AOC3CCNT1CDK9EPHA2KDR | |
| Tert-Butyl Formate SCHEMBL27768150 | 0.84 | AOC3 (0.38) | AOC3EPHA2KDREPHB4BAZ2A | |
| Tert-Butyl Formate SCHEMBL27789525 | 0.83 | AOC3 (0.40) | AOC3CCNT1CDK9EPHA2KDR | |
| Tert-Butyl Formate SCHEMBL27789538 | 0.83 | AOC3 (0.38) | AOC3GHSREPHA2KDREPHB4 | |
| Tert-Butyl Formate SCHEMBL27971425 | 0.81 | AOC3 (0.51) | AOC3EPHA2KDREPHB4BAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101616586-B | Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders | CYMABAY THERAPEUTICS INC | 2014-08-13 | — | — | CN | claimed |
| CN-101616586-B | Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders | CYMABAY THERAPEUTICS INC | 2014-08-13 | — | — | CN | disclosed |
| CN-102026636-B | Oxymethylene aryl compounds and uses thereof | METABOLEX INC | 2014-07-16 | — | — | CN | disclosed |
| CN-102026636-A | Oxymethylene aryl compounds and uses thereof | METABOLEX INC | 2011-04-20 | — | — | CN | disclosed |
| CN-101616586-A | The heterocyclic receptor agonists of treatment diabetes and metabolic disorder | METABOLEX INC | 2009-12-30 | — | — | CN | disclosed |