Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 16/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14089440 | 0.72 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2CHRM2ADRA2A | |
| SCHEMBL14089422 | 0.72 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2CHRM2ADRA2A | |
| SCHEMBL2279418 | 0.71 | SLC6A4 (0.77) | SLC6A4SLC6A3SLC6A2CHRM2ADRA2A | |
| SCHEMBL13011328 | 0.71 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2CHRM2ADRA2A | |
| SCHEMBL13011288 | 0.71 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2CHRM2ADRA2A | |
| SCHEMBL8167375 | 0.70 | SLC6A4 (0.67) | SLC6A4SLC6A3SLC6A2CHRM2ADRA2A | |
| SCHEMBL12235311 | 0.70 | SLC6A4 (0.57) | SLC6A4SLC6A3SLC6A2CHRM2ADRA2A | |
| SCHEMBL2739172 | 0.70 | SLC6A4 (0.67) | SLC6A4SLC6A3SLC6A2CHRM2ADRA2A | |
| SCHEMBL7187224 | 0.70 | SLC6A4 (0.67) | SLC6A4SLC6A3SLC6A2CHRM2ADRA2A | |
| SCHEMBL7184970 | 0.70 | SLC6A4 (0.67) | SLC6A4SLC6A3SLC6A2CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101626768-B | Synthesis, methods of using, and compositions of cycloalkylmethylamines | REVIVA PHARMACEUTICALS INC | 2013-08-21 | — | — | CN | disclosed |
| CN-101626768-A | Synthesis, methods of using, and compositions of cycloalkylmethylamines | REVIVA PHARMAMEUTICALS INC | 2010-01-13 | — | — | CN | disclosed |