SCHEMBL277683

SCHEMBL277683

O=Cc1ccc(-c2ccc(C=O)c(C=O)c2)cc1C=O

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
KMT2A Q03164 1/20 0.50
ERN1 O75460 15/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12084945 0.88 MEN1 (0.52) TDP1MEN1LMNATHRBBLM
SCHEMBL9404722 0.81 TDP1 (0.48) TDP1MEN1LMNATHRBBLM
SCHEMBL6124208 0.76 MEN1 (0.44) TDP1MEN1LMNATHRBBLM
SCHEMBL31081472 0.76 TYR (0.55) ERN1
SCHEMBL31556816 0.76 TDP1 (0.48) TDP1MEN1LMNATHRBBLM
SCHEMBL24086095 0.76 ERN1 (0.74) ERN1
SCHEMBL29682880 0.76 ERN1 (0.74) ERN1
SCHEMBL31099574 0.76 TYR (0.55) ERN1
SCHEMBL11869494 0.76 ALDH1A1 (0.52) TDP1MEN1LMNATHRBBLM
SCHEMBL29918523 0.76 ALDH1A1 (0.52) TDP1MEN1LMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250001368-A1 COVALENT ORGANIC FRAMEWORK MEMBRANES, METHODS AND USES THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-01-02 US claimed
CN-115957704-A Conjugated microporous polymer coated nano-silica microsphere, and preparation and application thereof 中国科学院大连化学物理研究所 2023-04-14 CN claimed
WO-2023009072-A2 COVALENT ORGANIC FRAMEWORK MEMBRANES, METHODS AND USES THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-02-02 WO claimed
WO-2022201203-A1 METAL FREE POROUS COVALENT ORGANIC NANOTUBES AND TOROIDS AND TO PREPARATION THEREOF INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IISER) KOLKATA (IN) 2022-09-29 WO claimed
US-4841009-A Substantially linear monomeric composition and liquid crystal polymeric compositions derived therefrom AMOCO CORPORATION (US) 1989-06-20 US claimed
JP-4266082-A None JP disclosed
US-20250001368-A1 COVALENT ORGANIC FRAMEWORK MEMBRANES, METHODS AND USES THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-01-02 US disclosed
CN-115957704-A Conjugated microporous polymer coated nano-silica microsphere, and preparation and application thereof 中国科学院大连化学物理研究所 2023-04-14 CN disclosed
WO-2023009072-A2 COVALENT ORGANIC FRAMEWORK MEMBRANES, METHODS AND USES THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-02-02 WO disclosed
CN-111777057-B Microporous carbon ball and preparation method and application thereof 中山大学 2022-12-27 CN disclosed
WO-2022201203-A1 METAL FREE POROUS COVALENT ORGANIC NANOTUBES AND TOROIDS AND TO PREPARATION THEREOF INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH (IISER) KOLKATA (IN) 2022-09-29 WO disclosed
US-20210341405-A1 SENSOR ENABLED BY CATALYTIC SYSTEM MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-11-04 US disclosed
US-5185419-A POLY(ARYLENEVINYLENESILOXANES) COMPOUNDS CONSORTIUM FUR ELEKTROCHEMISCHE GMBH (DE) 1993-02-09 US disclosed
JP-H04266082-A MANUFACTURE OF FLEXIBLE WIRING SUBSTRATE TORAY IND INC 1992-09-22 JP disclosed
US-5068292-A Reaction of monomers to form rigid polymer rods followed by reaction of matrix polymers in situ GENCORP INC. (US) 1991-11-26 US disclosed
EP-0442097-A2 Poly(arylenevinylene siloxanes) Consortium für elektrochemische Industrie GmbH (DE) 1991-08-21 EP disclosed
US-4841009-A Substantially linear monomeric composition and liquid crystal polymeric compositions derived therefrom AMOCO CORPORATION (US) 1989-06-20 US disclosed
EP-0136259-B1 4-HETEROCYCLYL-VINYL-4'-STYRYL-BIPHENYLS CIBA-GEIGY AG (CH) 1988-06-15 EP disclosed
US-4666627-A FLUORESCENT BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1987-05-19 US disclosed
EP-0136259-A1 4-Heterocyclyl-vinyl-4'-styryl-biphenyls CIBA-GEIGY AG (CH) 1985-04-03 EP disclosed