Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16304462 | 0.79 | CYP11B1 (0.72) | CYP11B1CYP11B2GAARAB9AMAPT | |
| SCHEMBL16731012 | 0.79 | CYP11B1 (0.48) | CYP11B1CYP11B2RAB9AMAPT | |
| SCHEMBL1951962 | 0.77 | CYP11B1 (0.79) | CYP11B1CYP11B2IDO1 | |
| SCHEMBL3873541 | 0.77 | CYP11B2 (0.56) | CYP11B1CYP11B2GAARAB9A | |
| SCHEMBL3882851 | 0.76 | CYP11B2 (0.56) | CYP11B1CYP11B2GAARAB9A | |
| SCHEMBL9046214 | 0.75 | CYP11B1 (0.60) | CYP11B1CYP11B2GAARAB9A | |
| SCHEMBL5351176 | 0.74 | GSK3B (0.49) | TDP1GAAMAPT | |
| SCHEMBL2399544 | 0.74 | CYP11B1 (0.52) | CYP11B1CYP11B2RAB9A | |
| SCHEMBL3819729 | 0.73 | CYP11B2 (0.78) | CYP11B1CYP11B2GAARAB9A | |
| SCHEMBL24131793 | 0.73 | MAPK10 (0.52) | CYP11B1CYP11B2GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101426778-A | N-substituted-azacyclylamines as histamine-3 antagonists | WYETH CORP (US) | 2009-05-06 | — | — | CN | disclosed |