Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56767 | 0.84 | ACVRL1 (0.58) | ACVRL1PIK3CD | |
| SCHEMBL27747195 | 0.78 | PIK3CD (0.48) | PIK3CD | |
| SCHEMBL2635291 | 0.72 | ACVRL1 (0.53) | ACVRL1 | |
| SCHEMBL27768187 | 0.70 | MAP4K4 (0.48) | PIK3CD | |
| SCHEMBL58580 | 0.70 | ACVRL1 (0.50) | ACVRL1PIK3CD | |
| SCHEMBL90826 | 0.69 | ACVRL1 (0.49) | ACVRL1 | |
| SCHEMBL66554 | 0.69 | ACVRL1 (0.49) | ACVRL1PIK3CD | |
| SCHEMBL66531 | 0.69 | ACVRL1 (0.55) | ACVRL1PIK3CD | |
| SCHEMBL83255 | 0.69 | ACVRL1 (0.58) | ACVRL1 | |
| SCHEMBL17002237 | 0.68 | GFER (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466710-A | Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis | BAYER HEALTHCARE LLC (US) | 2009-06-24 | — | — | CN | disclosed |