Methylpyrrolidone

Methylpyrrolidone

SCHEMBL27768356

CC(=O)c1ncc[nH]1.CN1CCCC1=O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.49
BRD2 P25440 1/20 0.49
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GLA P06280 1/20 0.33
KMT2A Q03164 1/20 0.33
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
TLK2 Q86UE8 1/20 0.30
KDM4C Q9H3R0 1/20 0.30
AVPR1A P37288 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98748 0.78
Bromide SCHEMBL28245258 0.76
Ammonia Solution, Strong SCHEMBL27514119 0.76
SCHEMBL4083095 0.76
SCHEMBL9154729 0.75 KMT2A (0.42) NPC1RAB9AHTTSMN1; SMN2GLA
Hydrochloric Acid SCHEMBL28307731 0.74 NPC1 (0.50) NPC1RAB9AHTTSMN1; SMN2GLA
Methylpyrrolidone SCHEMBL2243830 0.74 BRD4 (0.81) BRD4BRD2RAB9ASMN1; SMN2KMT2A
Urea SCHEMBL28133713 0.72 NPC1 (0.49) NPC1RAB9AHTTSMN1; SMN2GLA
Methylpyrrolidone SCHEMBL1801243 0.72 BRD4 (0.77) BRD4BRD2HTTKMT2A
Methylpyrrolidone SCHEMBL28608007 0.70 BRD4 (0.74) BRD4BRD2HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109206492-B Avian influenza synthetic peptide vaccine and preparation method thereof 中牧实业股份有限公司 2021-02-09 CN disclosed
CN-109206492-A A kind of bird flu synthetic peptide vaccine and preparation method thereof 中牧实业股份有限公司 2019-01-15 CN disclosed
CN-103880932-B Swine fever synthesized peptide vaccine and preparation method thereof ZHONGMU INDUSTRY CO., LTD. (CN) 2015-09-23 CN disclosed
CN-103880932-A Synthetic peptide vaccine for swine fever and preparation method thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2014-06-25 CN disclosed
CN-102485749-B Swine fever synthetic peptide vaccine and preparation method thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2014-06-04 CN disclosed
CN-102485749-A Swine fever synthetic peptide vaccine and preparation method thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2012-06-06 CN disclosed
CN-101628932-B Bird flu synthetic peptide vaccine and preparation method thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2012-06-06 CN disclosed
CN-101709080-B Synthetic peptide vaccine for resisting porcine circovirus and preparation method thereof CHINA ANIMAL HUSBANDRY INDUSTRY CO LTD 2012-06-06 CN disclosed
CN-101709080-A Synthetic peptide vaccine for resisting porcine circovirus and preparation method thereof CAHIC INDUSTRY CO LTD 2010-05-19 CN disclosed
CN-101628932-A Bird flu synthetic peptide vaccine and preparation method thereof CHINA ANIMAL HUSBANDRY INDUSTR 2010-01-20 CN disclosed