Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27790157 | 0.87 | GAA (0.49) | GAAMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL27768522 | 0.80 | MAPT (0.49) | GAAMAPTKMT2A | |
| Benzene SCHEMBL27768525 | 0.78 | GAA (0.47) | GAAMAPT | |
| SCHEMBL27768438 | 0.78 | MAPT (0.53) | GAAMAPT | |
| SCHEMBL12629105 | 0.78 | MAPT (0.47) | GAAMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL27790055 | 0.77 | MAPT (0.46) | GAAMAPTL3MBTL1MEN1CYP1A2 | |
| SCHEMBL27768464 | 0.75 | MAPT (0.53) | GAAMAPTMEN1CYP1A2CYP3A4 | |
| Aniline SCHEMBL27768445 | 0.74 | GAA (0.49) | GAAMAPT | |
| SCHEMBL27768506 | 0.74 | GAA (0.49) | GAAMAPTDRD2 | |
| SCHEMBL4999605 | 0.72 | GAA (0.56) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |