Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768438 | 0.80 | MAPT (0.53) | GAAMAPTKDM4E | |
| SCHEMBL27768522 | 0.76 | MAPT (0.49) | GAAMAPTKDM4ESMN1; SMN2SLC6A3 | |
| SCHEMBL12628272 | 0.76 | BRD4 (0.49) | GAAMAPTPTGER1PTGER4PTGER3 | |
| SCHEMBL27790157 | 0.76 | GAA (0.49) | GAAMAPTSMN1; SMN2RAB9A | |
| Aniline SCHEMBL27768445 | 0.76 | GAA (0.49) | GAAMAPTKDM4E | |
| Benzene SCHEMBL27768525 | 0.75 | GAA (0.47) | GAAMAPT | |
| SCHEMBL27768444 | 0.74 | GAA (0.47) | GAAMAPTDRD2 | |
| SCHEMBL27790055 | 0.73 | MAPT (0.46) | GAAMAPTKDM4ESMN1; SMN2SLC6A4 | |
| SCHEMBL7669210 | 0.73 | GAA (0.48) | GAAMAPTGLADRD2DRD3 | |
| SCHEMBL7669208 | 0.73 | GAA (0.48) | GAAMAPTGLADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |