Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27889178 | 0.79 | TRPA1 (0.47) | TRPA1DAOPTPN1HNF4ATUBB1 | |
| SCHEMBL9731902 | 0.77 | EGFR (0.44) | DAO | |
| SCHEMBL9834598 | 0.74 | CYP2A6 (0.58) | GRM4RELAPDGFRBPDGFRA | |
| SCHEMBL538252 | 0.74 | CYP2A6 (0.58) | GRM4RELAPDGFRBPDGFRA | |
| SCHEMBL538250 | 0.74 | CYP2A6 (0.58) | GRM4RELAPDGFRBPDGFRA | |
| (Z)-1,2-Diphenylethene SCHEMBL10659269 | 0.72 | TRPA1 (0.64) | TRPA1RELAAHRTTRALOX5 | |
| (Z)-1,2-Diphenylethene SCHEMBL10659275 | 0.72 | TRPA1 (0.64) | TRPA1RELAAHRTTRALOX5 | |
| (Z)-1,2-Diphenylethene SCHEMBL10658099 | 0.70 | TRPA1 (0.73) | TRPA1AHRTTRALOX5PTGS1 | |
| (Z)-1,2-Diphenylethene SCHEMBL10658094 | 0.70 | TRPA1 (0.73) | TRPA1AHRTTRALOX5PTGS1 | |
| SCHEMBL15902077 | 0.69 | DAO (0.43) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |