Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5829266 | 0.83 | MEN1 (0.38) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL5828931 | 0.83 | MEN1 (0.38) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL6697403 | 0.81 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL485946 | 0.80 | ANPEP (0.42) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL5829269 | 0.79 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL5828933 | 0.79 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL12481816 | 0.79 | ZDHHC7 (0.42) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL9231379 | 0.75 | HSD17B10 (0.37) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL1620937 | 0.74 | HPGD (0.38) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL8785206 | 0.72 | ZDHHC7 (0.39) | MEN1KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101481380-B | Thiofuran pyridazine compound, preparation thereof, pharmaceutical composition and uses thereof | ZHEJIANG MED XINCHANG PHARM | 2012-10-17 | — | — | CN | disclosed |
| CN-101481380-A | Thiofuran pyridazine compound, preparation thereof, pharmaceutical composition and uses thereof | ZHEJIANG MEDICINE CO LTD (CN) | 2009-07-15 | — | — | CN | disclosed |