Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5828931 | 1.00 | MEN1 (0.38) | MEN1KMT2ANPSR1MAPTHPGD | |
| SCHEMBL27768607 | 0.83 | MEN1 (0.38) | MEN1KMT2ANPSR1MAPTHPGD | |
| SCHEMBL5828933 | 0.82 | MEN1 (0.41) | MEN1KMT2ANPSR1MAPTHPGD | |
| SCHEMBL5829269 | 0.82 | MEN1 (0.41) | MEN1KMT2ANPSR1MAPTHPGD | |
| SCHEMBL6697403 | 0.81 | MEN1 (0.44) | MEN1KMT2ANPSR1MAPTHPGD | |
| SCHEMBL485946 | 0.79 | ANPEP (0.42) | MEN1KMT2ANPSR1MAPTHPGD | |
| SCHEMBL9231379 | 0.78 | HSD17B10 (0.37) | MEN1KMT2ANPSR1MAPTHPGD | |
| SCHEMBL22263552 | 0.72 | HRH3 (0.37) | MEN1KMT2AHPGDALDH1A1CTSK | |
| SCHEMBL18215144 | 0.71 | CTSK (0.42) | KMT2ACTSK | |
| SCHEMBL30556882 | 0.71 | PADI1 (0.45) | CTSKHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001904-B1 | Guanidine derivatives quinazoline and quinoline for use in the treatment of autoimmune diseases | ASTRAZENECA AB (SE) | 2006-02-21 | — | — | US | disclosed |