Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1118179 | 0.95 | GPR119 (0.44) | GPR119EPHA2KDREPHB4AOC3 | |
| Hydrochloric Acid SCHEMBL1118214 | 0.94 | GPR119 (0.43) | GPR119EPHA2KDREPHB4AOC3 | |
| Tert-Butyl Formate SCHEMBL27768398 | 0.92 | GPR119 (0.44) | GPR119EPHA2KDREPHB4AOC3 | |
| SCHEMBL27768127 | 0.92 | GPR119 (0.38) | GPR119EPHA2KDREPHB4AOC3 | |
| Acetic Acid SCHEMBL27973962 | 0.90 | GPR119 (0.45) | GPR119EPHA2KDREPHB4AOC3 | |
| SCHEMBL27789528 | 0.90 | GPR119 (0.38) | GPR119EPHA2KDREPHB4AOC3 | |
| SCHEMBL14874882 | 0.83 | GPR119 (0.45) | GPR119NPC1RAB9ASMN1; SMN2PTGS2 | |
| SCHEMBL3488433 | 0.81 | AOC3 (0.46) | GPR119EPHA2KDREPHB4AOC3 | |
| SCHEMBL27973840 | 0.81 | GPR119 (0.47) | GPR119NPC1RAB9ASMN1; SMN2PTGS2 | |
| Tert-Butyl Formate SCHEMBL27768084 | 0.80 | AOC3 (0.42) | GPR119EPHA2KDREPHB4AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026636-B | Oxymethylene aryl compounds and uses thereof | METABOLEX INC | 2014-07-16 | — | — | CN | disclosed |
| CN-102026636-A | Oxymethylene aryl compounds and uses thereof | METABOLEX INC | 2011-04-20 | — | — | CN | disclosed |
| CN-101616586-A | The heterocyclic receptor agonists of treatment diabetes and metabolic disorder | METABOLEX INC | 2009-12-30 | — | — | CN | disclosed |