Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.78 |
| ▸ | RAB9A | P51151 | 6/20 | 0.78 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | ADAMTS5 | Q9UNA0 | 7/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27790154 | 0.89 | KDM1A (0.75) | NPC1RAB9AHSP90AA1POLBKMT2A | |
| SCHEMBL2153766 | 0.89 | NPC1 (0.86) | NPC1RAB9AHSP90AA1POLBKMT2A | |
| SCHEMBL27790128 | 0.89 | NPC1 (0.86) | NPC1RAB9AHSP90AA1POLBKMT2A | |
| SCHEMBL4035597 | 0.89 | NPC1 (0.86) | NPC1RAB9AHSP90AA1POLBKMT2A | |
| SCHEMBL2153059 | 0.88 | NPC1 (1.00) | NPC1RAB9AHSP90AA1POLBKMT2A | |
| SCHEMBL1811300 | 0.87 | NPC1 (1.00) | NPC1RAB9AHSP90AA1POLBKMT2A | |
| SCHEMBL27768644 | 0.87 | HSP90AA1 (0.70) | NPC1RAB9AHSP90AA1POLBKMT2A | |
| SCHEMBL4037950 | 0.86 | NPC1 (0.85) | NPC1RAB9AHSP90AA1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL4037672 | 0.85 | NPC1 (0.84) | NPC1RAB9AHSP90AA1POLBKMT2A | |
| SCHEMBL2153962 | 0.85 | NPC1 (0.79) | NPC1RAB9AHSP90AA1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611009-A | Quinoline derivatives | CHRONOGEN INC (US) | 2009-12-23 | — | — | CN | claimed |