Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | KDM1A | O60341 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MITF | O75030 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27790154 | 0.95 | KDM1A (0.75) | HSP90AA1POLBKDM1AKDM4ENPC1 | |
| SCHEMBL23792594 | 0.91 | HSP90AA1 (0.75) | HSP90AA1POLBKDM1AKDM4ENPC1 | |
| SCHEMBL27768660 | 0.91 | HSP90AA1 (0.75) | HSP90AA1POLBKDM1AKDM4ENPC1 | |
| SCHEMBL2153116 | 0.90 | HSP90AA1 (0.76) | HSP90AA1POLBKDM1AKDM4ENPC1 | |
| SCHEMBL31672845 | 0.88 | ADAMTS5 (0.79) | HSP90AA1POLBKDM1AKDM4ENPC1 | |
| SCHEMBL2153202 | 0.88 | ADAMTS5 (0.79) | HSP90AA1POLBKDM1AKDM4ENPC1 | |
| SCHEMBL27768652 | 0.87 | NPC1 (0.78) | HSP90AA1POLBKDM1AKDM4ENPC1 | |
| SCHEMBL30876565 | 0.86 | KDM1A (0.81) | HSP90AA1POLBKDM1AKDM4ENPC1 | |
| SCHEMBL2153092 | 0.86 | KDM1A (0.81) | HSP90AA1POLBKDM1AKDM4ENPC1 | |
| SCHEMBL30876632 | 0.85 | HSP90AA1 (0.73) | HSP90AA1POLBKDM1AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611009-A | Quinoline derivatives | CHRONOGEN INC (US) | 2009-12-23 | — | — | CN | claimed |